The card will sometimes plug and play but will not work. This is the setup utility that sets the I/O address and IRQ on the card. Start the system and write down a few free I/O's and IRQ's. Install the card and cancel plug and play if it comes up. Run the utility from a prompt and set the I/O and IRQ to a free one on the system. In windows use add/remove hardware to add the card and install it as a Novell/Anthem NE2000 compatible. I have used it in Win 95 and 98 and it should work in Netware as well. Not sure about DOS.